人 APBB2 (NM_001166050) cDNA克隆

Accession: NM_001166050
基因名称: APBB2
基因别名: FE65L; FE65L1
基因描述: Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 2 (APBB2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2277 (查看编码区序列)
翻译后氨基酸长度: 758 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a.
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G100281 人 APBB2 (NM_001166050) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]