人 APBB2 (NM_001166051) cDNA克隆

基本信息

Accession: NM_001166051
基因名称: APBB2
基因别名: FE65L; FE65L1
基因描述: Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 2 (APBB2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 633 (查看编码区序列)
翻译后氨基酸长度: 210 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the presence and absence of exons in the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The resulting isoform (d) is significantly shorter at the N-terminus, compared to isoform a. Variants 4, 5, 6 and 7 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G100282 人 APBB2 (NM_001166051) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 APBB2 (NM_004307) cDNA克隆 transcript variant 1
人 APBB2 (NM_001166050) cDNA克隆 transcript variant 2
人 APBB2 (NM_173075) cDNA克隆 transcript variant 3
人 APBB2 (NM_001166051) cDNA克隆 transcript variant 4
人 APBB2 (NM_001166052) cDNA克隆 transcript variant 5
人 APBB2 (NM_001166053) cDNA克隆 transcript variant 6
人 APBB2 (NM_001166054) cDNA克隆 transcript variant 7

基因简介

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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