人 RAD54B (NM_001205262) cDNA克隆

Accession: NM_001205262
基因名称: RAD54B
基因别名: RDH54
基因描述: Homo sapiens RAD54 homolog B (S. cerevisiae) (RAD54B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 354 (查看编码区序列)
翻译后氨基酸长度: 117 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks several coding exons and uses an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1.
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G102608 人 RAD54B (NM_001205262) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]