人 RAD51B (NM_133510) cDNA克隆

基本信息

Accession: NM_133510
基因名称: RAD51B
基因别名: REC2; R51H2; RAD51L1
基因描述: Homo sapiens RAD51 paralog B (RAD51B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1053 (查看编码区序列)
翻译后氨基酸长度: 350 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate exon at the 3' end compared to the longest variant (3). The resulting isoform (2) has a distinct and shorter C-terminus, as compared to isoform 3.

订购信息

产品编号 产品名称 载体 规格 价格
G106380 人 RAD51B (NM_133510) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RAD51B (NM_002877) cDNA克隆 transcript variant 1
人 RAD51B (NM_133510) cDNA克隆 transcript variant 2
人 RAD51B (NM_133509) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]

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