人 RELA (NM_001145138) cDNA克隆

Accession: NM_001145138
基因名称: RELA
基因别名: p65; NFKB3
基因描述: Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1647 (查看编码区序列)
翻译后氨基酸长度: 548 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at one of the coding exons compared to transcript variant 1. This results in a shorter isoform (2) missing a 3 aa segment compared to isoform 1.
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G103627 人 RELA (NM_001145138) cDNA克隆 pDONR223 2ug质粒 点击询价

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]