人 RELA (NM_001243984) cDNA克隆

基本信息

Accession: NM_001243984
基因名称: RELA
基因别名: p65; NFKB3
基因描述: Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1449 (查看编码区序列)
翻译后氨基酸长度: 482 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice site at the 5' end of the last exon compared to variant 1. The resulting isoform (3) lacks an alternate internal segment compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103628 人 RELA (NM_001243984) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RELA (NM_021975) cDNA克隆 transcript variant 1
人 RELA (NM_001145138) cDNA克隆 transcript variant 2
人 RELA (NM_001243984) cDNA克隆 transcript variant 3
人 RELA (NM_001243985) cDNA克隆 transcript variant 4

基因简介

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

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