人 RELA (NM_001243985) cDNA克隆

基本信息

Accession: NM_001243985
基因名称: RELA
基因别名: p65; NFKB3
基因描述: Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1347 (查看编码区序列)
翻译后氨基酸长度: 448 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate internal in-frame segment in the last exon compared to variant 1. The resulting isoform (4) lacks an alternate internal segment compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103629 人 RELA (NM_001243985) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RELA (NM_021975) cDNA克隆 transcript variant 1
人 RELA (NM_001145138) cDNA克隆 transcript variant 2
人 RELA (NM_001243984) cDNA克隆 transcript variant 3
人 RELA (NM_001243985) cDNA克隆 transcript variant 4

基因简介

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

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