人 RBM5 (NM_005778) cDNA克隆

Accession: NM_005778
基因名称: RBM5
基因别名: G15; H37; RMB5; LUCA15
基因描述: Homo sapiens RNA binding motif protein 5 (RBM5), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2448 (查看编码区序列)
翻译后氨基酸长度: 815 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and is protein coding.
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G104095 人 RBM5 (NM_005778) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]