人 RBM14 (NM_001198837) cDNA克隆

Accession: NM_001198837
基因名称: RBM14
基因别名: SIP; COAA; PSP2; SYTIP1; TMEM137
基因描述: Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.
种属: Human
CDS区长度: 360 (查看编码区序列)
翻译后氨基酸长度: 119 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (3, also known as CoAR or coactivator regulator) with a distinct and shorter C-terminus compared to isoform 1.
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G104256 人 RBM14 (NM_001198837) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]