人 TLK1 (NM_012290) cDNA克隆

Accession: NM_012290
基因名称: TLK1
基因别名: PKU-beta
基因描述: Homo sapiens tousled-like kinase 1 (TLK1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2301 (查看编码区序列)
翻译后氨基酸长度: 766 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G104386 人 TLK1 (NM_012290) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]