人 TLK2 (NM_006852) cDNA克隆

Accession: NM_006852
基因名称: TLK2
基因别名: HsHPK; PKU-ALPHA
基因描述: Homo sapiens tousled-like kinase 2 (TLK2), transcript variant A, mRNA.
种属: Human
CDS区长度: 2253 (查看编码区序列)
翻译后氨基酸长度: 750 (查看氨基酸序列)
Transcript Variant: This variant (A) lacks an alternate in-frame exon in the 3' coding region compared to variant C. The encoded protein (isoform A) is shorter than isoform C.
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G115769 人 TLK2 (NM_006852) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]