人 TLK1 (NM_001136554) cDNA克隆

基本信息

Accession: NM_001136554
基因名称: TLK1
基因别名: PKU-beta
基因描述: Homo sapiens tousled-like kinase 1 (TLK1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2157 (查看编码区序列)
翻译后氨基酸长度: 718 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding region, and uses a downstream start codon, compared to variant 1, resulting in a shorter protein (isoform 2).

订购信息

产品编号 产品名称 载体 规格 价格
G104387 人 TLK1 (NM_001136554) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TLK1 (NM_012290) cDNA克隆 transcript variant 1
人 TLK1 (NM_001136554) cDNA克隆 transcript variant 2
人 TLK1 (NM_001136555) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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