人 PPM1B (NM_002706) cDNA克隆

Accession: NM_002706
基因名称: PPM1B
基因别名: PP2CB; PP2CBETA; PPC2BETAX; PP2C-beta-X
基因描述: Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1440 (查看编码区序列)
翻译后氨基酸长度: 479 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G105252 人 PPM1B (NM_002706) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]