人 PPM1B (NM_177969) cDNA克隆

基本信息

Accession: NM_177969
基因名称: PPM1B
基因别名: PP2CB; PP2CBETA; PPC2BETAX; PP2C-beta-X
基因描述: Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 579 (查看编码区序列)
翻译后氨基酸长度: 192 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an internal segment, which includes a part of the coding region, as compared to variant 1. The translation begins at a downstream start codon, resulting in an isoform (3) that has a shorter N-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G105254 人 PPM1B (NM_177969) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PPM1B (NM_002706) cDNA克隆 transcript variant 1
人 PPM1B (NM_177968) cDNA克隆 transcript variant 2
人 PPM1B (NM_177969) cDNA克隆 transcript variant 3
人 PPM1B (NM_001033556) cDNA克隆 transcript variant 4
人 PPM1B (NM_001033557) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]

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