人 SETDB1 (NM_001145415) cDNA克隆

Accession: NM_001145415
基因名称: SETDB1
基因别名: ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
基因描述: Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3876 (查看编码区序列)
翻译后氨基酸长度: 1291 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G106467 人 SETDB1 (NM_001145415) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]