人 SETDB1 (NM_001243491) cDNA克隆

基本信息

Accession: NM_001243491
基因名称: SETDB1
基因别名: ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
基因描述: Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1194 (查看编码区序列)
翻译后氨基酸长度: 397 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site in the 5' UTR, differs in the 3' UTR and lacks a large portion of the coding region, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus and lacks the histone methyltransferase and SET domains, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106469 人 SETDB1 (NM_001243491) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SETDB1 (NM_001145415) cDNA克隆 transcript variant 1
人 SETDB1 (NM_012432) cDNA克隆 transcript variant 2
人 SETDB1 (NM_001243491) cDNA克隆 transcript variant 3

基因简介

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]

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