人 SETDB2 (NM_001160308) cDNA克隆

Accession: NM_001160308
基因名称: SETDB2
基因别名: CLLD8; CLLL8; KMT1F; C13orf4
基因描述: Homo sapiens SET domain, bifurcated 2 (SETDB2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2124 (查看编码区序列)
翻译后氨基酸长度: 707 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
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G115716 人 SETDB2 (NM_001160308) cDNA克隆 pDONR223 2ug质粒 点击询价

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM, Mar 2008]