人 EDNRA (NM_001166055) cDNA克隆

基本信息

Accession: NM_001166055
基因名称: EDNRA
基因别名: ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR
基因描述: Homo sapiens endothelin receptor type A (EDNRA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 957 (查看编码区序列)
翻译后氨基酸长度: 318 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as ET-ARdelta3,4) lacks two alternate exons, resulting in the loss of an in-frame segment of the central coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G106607 人 EDNRA (NM_001166055) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EDNRA (NM_001957) cDNA克隆 transcript variant 1
人 EDNRA (NM_001166055) cDNA克隆 transcript variant 2
人 EDNRA (NM_001256283) cDNA克隆 transcript variant 3

基因简介

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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