人 EDNRA (NM_001957) cDNA克隆

Accession: NM_001957
基因名称: EDNRA
基因别名: ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR
基因描述: Homo sapiens endothelin receptor type A (EDNRA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
Transcript Variant: This variant (1, also known as ET-AR) represents the longest transcript and encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G106608 人 EDNRA (NM_001957) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]