人 EDNRA (NM_001256283) cDNA克隆

Accession: NM_001256283
基因名称: EDNRA
基因别名: ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR
基因描述: Homo sapiens endothelin receptor type A (EDNRA), transcript variant 3, mRNA.
种属: Human
CDS区长度: 609 (查看编码区序列)
翻译后氨基酸长度: 202 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a.
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G106609 人 EDNRA (NM_001256283) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]