人 CHMP2B (NM_001244644) cDNA克隆

基本信息

Accession: NM_001244644
基因名称: CHMP2B
基因别名: DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5
基因描述: Homo sapiens charged multivesicular body protein 2B (CHMP2B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 519 (查看编码区序列)
翻译后氨基酸长度: 172 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, compared to variant 1. The resulting predicted protein (isoform 2) is shorter when it is compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G108224 人 CHMP2B (NM_001244644) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CHMP2B (NM_014043) cDNA克隆 transcript variant 1
人 CHMP2B (NM_001244644) cDNA克隆 transcript variant 2

基因简介

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]

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