人 CHMP3 (NM_016079) cDNA克隆

Accession: NM_016079
基因名称: CHMP3
基因别名: NEDF; VPS24; CGI-149
基因描述: Homo sapiens charged multivesicular body protein 3 (CHMP3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 669 (查看编码区序列)
翻译后氨基酸长度: 222 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as Vps24alpha).
产品编号 产品名称 载体 规格 价格
G108282 人 CHMP3 (NM_016079) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]