人 CHMP3 (NM_001193517) cDNA克隆

基本信息

Accession: NM_001193517
基因名称: CHMP3
基因别名: NEDF; VPS24; CGI-149
基因描述: Homo sapiens charged multivesicular body protein 3 (CHMP3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 549 (查看编码区序列)
翻译后氨基酸长度: 182 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G108283 人 CHMP3 (NM_001193517) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CHMP3 (NM_016079) cDNA克隆 transcript variant 1
人 CHMP3 (NM_001005753) cDNA克隆 transcript variant 2
人 CHMP3 (NM_001193517) cDNA克隆 transcript variant 3

基因简介

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]

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