人 MAP2K5 (NM_002757) cDNA克隆

基本信息

Accession: NM_002757
基因名称: MAP2K5
基因别名: MEK5; MAPKK5; PRKMK5; HsT17454
基因描述: Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1317 (查看编码区序列)
翻译后氨基酸长度: 438 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (B) has the same N- and C-termini but is shorter compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G111149 人 MAP2K5 (NM_002757) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MAP2K5 (NM_145160) cDNA克隆 transcript variant 1
人 MAP2K5 (NM_002757) cDNA克隆 transcript variant 2
人 MAP2K5 (NM_001206804) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]

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