人 CARD14 (NM_001257970) cDNA克隆

Accession: NM_001257970
基因名称: CARD14
基因别名: PRP; PSS1; BIMP2; CARMA2; PSORS2
基因描述: Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2223 (查看编码区序列)
翻译后氨基酸长度: 740 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks several exons and its transcription extends past a splice site that is used in variant 1. The encoded isoform 3 has a shorter C-terminus, compared to isoform 1.
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G112767 人 CARD14 (NM_001257970) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]