人 ATF3 (NM_001040619) cDNA克隆

基本信息

Accession: NM_001040619
基因名称: ATF3
基因描述: Homo sapiens activating transcription factor 3 (ATF3), transcript variant 4, mRNA.
种属: Human
CDS区长度: 408 (查看编码区序列)
翻译后氨基酸长度: 135 (查看氨基酸序列)
Transcript Variant: This variant (4, also known as deltaZip2a) contains an alternate terminal exon, and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2, also known as deltaZip2) has a distinct and shorter C-terminus, compared to isoform 1. Isoform 2 lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter.

订购信息

产品编号 产品名称 载体 规格 价格
G113254 人 ATF3 (NM_001040619) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ATF3 (NM_001674) cDNA克隆 transcript variant 1
人 ATF3 (NM_001030287) cDNA克隆 transcript variant 3
人 ATF3 (NM_001040619) cDNA克隆 transcript variant 4
人 ATF3 (NM_001206484) cDNA克隆 transcript variant 5
人 ATF3 (NM_001206486) cDNA克隆 transcript variant 7
人 ATF3 (NM_001206488) cDNA克隆 transcript variant 8

基因简介

This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]

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