人 ATF2 (NM_001880) cDNA克隆

Accession: NM_001880
基因名称: ATF2
基因别名: HB16; CREB2; TREB7; CRE-BP1
基因描述: Homo sapiens activating transcription factor 2 (ATF2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1518 (查看编码区序列)
翻译后氨基酸长度: 505 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 2 encode the same isoform.
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G118683 人 ATF2 (NM_001880) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]