人 ATF2 (NM_001256093) cDNA克隆

基本信息

Accession: NM_001256093
基因名称: ATF2
基因别名: HB16; CREB2; TREB7; CRE-BP1
基因描述: Homo sapiens activating transcription factor 2 (ATF2), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1125 (查看编码区序列)
翻译后氨基酸长度: 374 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an internal exon, and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. This results in translation initiation from another start site, and a shorter isoform (4) with distinct N- and C- termini compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118687 人 ATF2 (NM_001256093) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ATF2 (NM_001880) cDNA克隆 transcript variant 1
人 ATF2 (NM_001256090) cDNA克隆 transcript variant 2
人 ATF2 (NM_001256091) cDNA克隆 transcript variant 3
人 ATF2 (NM_001256092) cDNA克隆 transcript variant 4
人 ATF2 (NM_001256093) cDNA克隆 transcript variant 5
人 ATF2 (NM_001256094) cDNA克隆 transcript variant 6

基因简介

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

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