人 MAP4K5 (NM_006575) cDNA克隆

Accession: NM_006575
基因名称: MAP4K5
基因别名: KHS; GCKR; KHS1; MAPKKKK5
基因描述: Homo sapiens mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2541 (查看编码区序列)
翻译后氨基酸长度: 846 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1 and 2 encode the same isoform.
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G114075 人 MAP4K5 (NM_006575) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]