人 CLEC1B (NM_001099431) cDNA克隆

Accession: NM_001099431
基因名称: CLEC1B
基因别名: CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik
基因描述: Homo sapiens C-type lectin domain family 1, member B (CLEC1B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 591 (查看编码区序列)
翻译后氨基酸长度: 196 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a.
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G114664 人 CLEC1B (NM_001099431) cDNA克隆 pDONR223 2ug质粒 点击询价

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]