人 RAD21 (NM_006265) cDNA克隆

Accession: NM_006265
基因名称: RAD21
基因别名: HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21
基因描述: Homo sapiens RAD21 homolog (S. pombe) (RAD21), mRNA.
种属: Human
CDS区长度: 1896 (查看编码区序列)
翻译后氨基酸长度: 631 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G116873 人 RAD21 (NM_006265) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]