人 CLEC12A (NM_201623) cDNA克隆

Accession: NM_201623
基因名称: CLEC12A
基因别名: CLL1; MICL; CLL-1; DCAL-2
基因描述: Homo sapiens C-type lectin domain family 12, member A (CLEC12A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 699 (查看编码区序列)
翻译后氨基酸长度: 232 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2, also referred to as beta), compared to isoform 1.
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G117223 人 CLEC12A (NM_201623) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]