人 SMG6 (NM_017575) cDNA克隆

基本信息

Accession: NM_017575
基因名称: SMG6
基因别名: EST1A; SMG-6; C17orf31; hSMG5/7a
基因描述: Homo sapiens SMG6 nonsense mediated mRNA decay factor (SMG6), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4260 (查看编码区序列)
翻译后氨基酸长度: 1419 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G120186 人 SMG6 (NM_017575) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SMG6 (NM_017575) cDNA克隆 transcript variant 1
人 SMG6 (NM_001256827) cDNA克隆 transcript variant 3
人 SMG6 (NM_001256828) cDNA克隆 transcript variant 4
人 SMG6 (NM_001282326) cDNA克隆 transcript variant 5

基因简介

This gene encodes a protein which is part of the telomerase ribonucleoprotein complex and binds single-stranded DNA found at the telomeres, but the product of this gene also participates in the nonsense-mediated mRNA decay (NMD) pathway. The encoded protein contains two binding sites for components of the exon junction complex (EJC); interaction between the encoded protein and the EJC is necessary for NMD activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

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