人 PAK1 (NM_002576) cDNA克隆

Accession: NM_002576
基因名称: PAK1
基因别名: PAKalpha
基因描述: Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1638 (查看编码区序列)
翻译后氨基酸长度: 545 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks a coding exon in the 3' region, as compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
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G123197 人 PAK1 (NM_002576) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]