人 RASGRP2 (NM_001098670) cDNA克隆

基本信息

Accession: NM_001098670
基因名称: RASGRP2
基因别名: CDC25L; CALDAG-GEFI
基因描述: Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1830 (查看编码区序列)
翻译后氨基酸长度: 609 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 4 all encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G123203 人 RASGRP2 (NM_001098670) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RASGRP2 (NM_153819) cDNA克隆 transcript variant 2
人 RASGRP2 (NM_001098670) cDNA克隆 transcript variant 3
人 RASGRP2 (NM_001098671) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

相关产品