人 RGS11 (NM_001286486) cDNA克隆

Accession: NM_001286486
基因名称: RGS11
基因别名: RS11
基因描述: Homo sapiens regulator of G-protein signaling 11 (RGS11), transcript variant 4, mRNA.
种属: Human
CDS区长度: 852 (查看编码区序列)
翻译后氨基酸长度: 283 (查看氨基酸序列)
Transcript Variant: This variant (4) uses an alternate splice junction at the 3' end of the first exon and lacks two alternate exons compared to variant 1. The resulting isoform (4) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform 1.
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G125146 人 RGS11 (NM_001286486) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]