人 ADARB1 (NM_001112) cDNA克隆

Accession: NM_001112
基因名称: ADARB1
基因别名: RED1; ADAR2; DRABA2; DRADA2
基因描述: Homo sapiens adenosine deaminase, RNA-specific, B1 (ADARB1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2106 (查看编码区序列)
翻译后氨基酸长度: 701 (查看氨基酸序列)
Transcript Variant: This variant (1), also known as ADAR2a-L1 or DRADA2a, lacks the ALU cassette insert and contains the long C-terminal region, as compared to variant 2. The resulting isoform (1), also known as hRED1-Short, lacks an internal segment, compared to isoform 2.
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G126739 人 ADARB1 (NM_001112) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]