小鼠 Adarb1 (NM_001024837) cDNA克隆

Accession: NM_001024837
基因名称: Adarb1
基因别名: Red1; Adar2; AW124433; AW558573; BB220382; D10Bwg0447e; 1700057H01Rik
基因描述: Mus musculus adenosine deaminase, RNA-specific, B1 (Adarb1), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 2136 (查看编码区序列)
翻译后氨基酸长度: 711 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a longer isoform (2) containing a 10 aa segment that is missing in isoform 1.
产品编号 产品名称 载体 规格 价格
G127697 小鼠 Adarb1 (NM_001024837) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]