人 YAP1 (NM_001130145) cDNA克隆

Accession: NM_001130145
基因名称: YAP1
基因别名: YAP; YKI; YAP2; YAP65
基因描述: Homo sapiens Yes-associated protein 1 (YAP1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1515 (查看编码区序列)
翻译后氨基酸长度: 504 (查看氨基酸序列)
Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 9. The encoded protein (isoform 1) represents the YAP1-2gamma isoform described in Figure 3 of PMID: 22939869. It is shorter, compared to isoform 9.
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G126775 人 YAP1 (NM_001130145) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]