人 YAP1 (NM_001282101) cDNA克隆

Accession: NM_001282101
基因名称: YAP1
基因别名: YAP; YKI; YAP2; YAP65
基因描述: Homo sapiens Yes-associated protein 1 (YAP1), transcript variant 9, mRNA.
种属: Human
CDS区长度: 1527 (查看编码区序列)
翻译后氨基酸长度: 508 (查看氨基酸序列)
Transcript Variant: This variant (9) represents the longest transcript and encodes the longest isoform (9). The encoded protein represents the YAP1-2delta isoform described in Figure 3 of PMID: 22939869.
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G126783 人 YAP1 (NM_001282101) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]