人 YAP1 (NM_006106) cDNA克隆

基本信息

Accession: NM_006106
基因名称: YAP1
基因别名: YAP; YKI; YAP2; YAP65
基因描述: Homo sapiens Yes-associated protein 1 (YAP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1353 (查看编码区序列)
翻译后氨基酸长度: 450 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site and lacks two alternate exons in the coding region, compared to variant 9. The encoded protein (isoform 2) represents the YAP1-1alpha isoform described in Figure 3 of PMID: 22939869. It is shorter, compared to isoform 9.

订购信息

产品编号 产品名称 载体 规格 价格
G126776 人 YAP1 (NM_006106) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 YAP1 (NM_001130145) cDNA克隆 transcript variant 1
人 YAP1 (NM_006106) cDNA克隆 transcript variant 2
人 YAP1 (NM_001195044) cDNA克隆 transcript variant 3
人 YAP1 (NM_001195045) cDNA克隆 transcript variant 4
人 YAP1 (NM_001282098) cDNA克隆 transcript variant 5
人 YAP1 (NM_001282097) cDNA克隆 transcript variant 6
人 YAP1 (NM_001282099) cDNA克隆 transcript variant 7
人 YAP1 (NM_001282100) cDNA克隆 transcript variant 8
人 YAP1 (NM_001282101) cDNA克隆 transcript variant 9

基因简介

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

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