人 RGS7BP (NM_001271890) cDNA克隆

Accession: NM_001271890
基因名称: RGS7BP
基因别名: R7BP
基因描述: Homo sapiens regulator of G-protein signaling 7 binding protein (RGS7BP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 375 (查看编码区序列)
翻译后氨基酸长度: 124 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks two alternate exons in the 5' coding region and uses a downstream start codon compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1.
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G151990 人 RGS7BP (NM_001271890) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]