人 SHMT2 (NM_001166356) cDNA克隆

基本信息

Accession: NM_001166356
基因名称: SHMT2
基因别名: GLYA; SHMT
基因描述: Homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1485 (查看编码区序列)
翻译后氨基酸长度: 494 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G102172 人 SHMT2 (NM_001166356) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SHMT2 (NM_005412) cDNA克隆 transcript variant 1
人 SHMT2 (NM_001166356) cDNA克隆 transcript variant 2
人 SHMT2 (NM_001166357) cDNA克隆 transcript variant 3
人 SHMT2 (NM_001166358) cDNA克隆 transcript variant 4
人 SHMT2 (NM_001166359) cDNA克隆 transcript variant 5

基因简介

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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