人 SHMT1 (NM_001281786) cDNA克隆

基本信息

Accession: NM_001281786
基因名称: SHMT1
基因别名: SHMT; CSHMT
基因描述: Homo sapiens serine hydroxymethyltransferase 1 (soluble) (SHMT1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1038 (查看编码区序列)
翻译后氨基酸长度: 345 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate 5' exon structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111578 人 SHMT1 (NM_001281786) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SHMT1 (NM_004169) cDNA克隆 transcript variant 1
人 SHMT1 (NM_148918) cDNA克隆 transcript variant 2
人 SHMT1 (NM_001281786) cDNA克隆 transcript variant 3

基因简介

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

相关产品