人 SHMT1 (NM_148918) cDNA克隆

基本信息

Accession: NM_148918
基因名称: SHMT1
基因别名: SHMT; CSHMT
基因描述: Homo sapiens serine hydroxymethyltransferase 1 (soluble) (SHMT1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1335 (查看编码区序列)
翻译后氨基酸长度: 444 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111577 人 SHMT1 (NM_148918) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SHMT1 (NM_004169) cDNA克隆 transcript variant 1
人 SHMT1 (NM_148918) cDNA克隆 transcript variant 2
人 SHMT1 (NM_001281786) cDNA克隆 transcript variant 3

基因简介

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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