人 UBE2A (NM_003336) cDNA克隆

Accession: NM_003336
基因名称: UBE2A
基因别名: UBC2; HHR6A; MRXSN; RAD6A; MRXS30
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2A (UBE2A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 459 (查看编码区序列)
翻译后氨基酸长度: 152 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G103137 人 UBE2A (NM_003336) cDNA克隆 pDONR223 2ug质粒 点击询价

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]