人 UBE2H (NM_001202498) cDNA克隆

Accession: NM_001202498
基因名称: UBE2H
基因别名: GID3; UBC8; UBCH; UBCH2; E2-20K
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2H (UBE2H), transcript variant 3, mRNA.
种属: Human
CDS区长度: 342 (查看编码区序列)
翻译后氨基酸长度: 113 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate splice site in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (3) has a shorter N-terminus, as compared to isoform 1.
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G107938 人 UBE2H (NM_001202498) cDNA克隆 pDONR223 2ug质粒 点击询价

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Feb 2011]