人 UBE2G2 (NM_001202489) cDNA克隆

Accession: NM_001202489
基因名称: UBE2G2
基因别名: UBC7
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2G 2 (UBE2G2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 288 (查看编码区序列)
翻译后氨基酸长度: 95 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (3) has a shorter N-terminus, as compared to isoform 1.
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G103215 人 UBE2G2 (NM_001202489) cDNA克隆 pDONR223 2ug质粒 点击询价

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]