人 ACVR1B (NM_020328) cDNA克隆

Accession: NM_020328
基因名称: ACVR1B
基因别名: ALK4; SKR2; ACTRIB; ACVRLK4
基因描述: Homo sapiens activin A receptor, type IB (ACVR1B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1641 (查看编码区序列)
翻译后氨基酸长度: 546 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame exon, compared to variant 1. The encoded isoform (c) is longer than isoform a.
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G104039 人 ACVR1B (NM_020328) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]