人 ACVR1C (NM_001111032) cDNA克隆

基本信息

Accession: NM_001111032
基因名称: ACVR1C
基因别名: ALK7; ACVRLK7
基因描述: Homo sapiens activin A receptor, type IC (ACVR1C), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1242 (查看编码区序列)
翻译后氨基酸长度: 413 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the coding region, compared to variant 1. The resulting isoform (3), also known as sALK7a, lacks the transmembrane and GS domains, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G115100 人 ACVR1C (NM_001111032) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ACVR1C (NM_145259) cDNA克隆 transcript variant 1
人 ACVR1C (NM_001111031) cDNA克隆 transcript variant 2
人 ACVR1C (NM_001111032) cDNA克隆 transcript variant 3
人 ACVR1C (NM_001111033) cDNA克隆 transcript variant 4

基因简介

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

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